| || 221054BR |
| || Scientist Medicinal Chemistry-Novartis Institute for Tropical Diseases |
| || NIBR |
| || Global Discovery Chemistry |
| || USA |
| || Emeryville, CA |
| || NIBRI |
| || Research & Development |
| || Full Time |
| || Regular |
| || The Novartis Institute for Tropical Diseases (NITD), relocated to Emeryville, California, is dedicated to fighting parasitic infectious diseases of high medical need in a dynamic working environment. NITD is an independent Institute within the Novartis Institutes for Biomedical Research (NIBR), and as such has full access to NIBR know-how and resources including the chemists of the Global Discovery Chemistry group and the Infectious Diseases drug discovery teams (antiviral and antibacterial) co-located in Emeryville. NITD is renowned for applying cutting-edge technologies to the discovery of high quality clinical candidates for the treatment of neglected diseases. The Institute has a highly collaborative culture and has close links with academic centers of excellence and a broad range of non-governmental and philanthropic organizations around the globe (Wellcome Trust, Bill and Melinda Gates Foundation, Medicines for Malaria Venture and Drugs for Neglected Diseases Initiative).
About NIBR Global Medicinal Chemistry: The Tropical Diseases Medicinal Chemistry group is a part of the Global Discovery Chemistry community within Novartis. The groups’ primary responsibilities are the design and synthesis of biologically active low molecular weight compounds as potential drugs for the treatment of viral, microbial, and parasitic diseases. Working closely with colleagues from other functional areas the Global Discovery Chemistry group focuses on the discovery of new medicines through the optimization of potency, selectivity, ADME and physical properties. The groups’ capabilities include purification, fragment and structure-based drug design, property-based drug design, compound library and parallel compound synthesis design, hit evaluation and follow-up from HTS campaigns.
About the position:
The successful candidate will help perform innovative research in the preparation of novel organic molecules to aid in the discovery and development of new therapeutically relevant compounds. Specifically, the candidate will:
• Perform design and synthesis of biologically active compounds, document methods and create data presentations
• Characterize compounds using analytical instrumentation such as HPLC, LCMS, IR and NMR
• Present scientific results at team meetings
• Maintain laboratory notebooks
• Write experimental protocols and prepare internal reports.
| || The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. |
| || • BS or MS degree in Chemistry with a solid understanding of organic chemistry
• 0 to 4 years organic chemistry laboratory experience synthesizing small molecules.
• Experienced in the use of HPLC, LCMS, IR and NMR instrumentation and the interpretation of data generated as required for the analysis and characterization of organic molecules.
• The ability to function within a multi-disciplinary scientific research team
• Good verbal and written communication skills